Diabetes Mellitus Prevention

"All the money in the world can't buy you back good health." --Reba McEntire




Collaborative Education

Together with the group of Prof. Eicke Latz and iGEM Dresden, we plan to educate about possibilities that individuals have in order to prevent diseases like type 2 diabetes and adipositas.

Overall, there is more than enough evidence that western life-style, in its sedentary, high-sugar, high-unsaturated fatty acids, high-cholesterol, high-salt and low-fibre way, promotes the development of inflammatory and chronic diseases [1,2]. Although, especially in research environment, this fact is known, knowledge transfer to the public has not been sufficient enough to adequately spread the notion of a balanced nutrition to prevent potentially fatal diseases, such as Diabetes Mellitus and Morbus Crohn[1,2,3,4].

As we, iGEM Tübingen, want to target Type 2 DM treatment and iGEM Dresden works on the development of a new sugar substitution, we want to share our knowledge with the public and start a preventive project.

As our projects are highly intertwined with the use of synthetic biology and the design and use of GMOs (Genetically modified organisms), we want to combine education about healthy nutrition, which prevents diseases like Diabetes from occurring solely because of malnutrition, and the usage of GMO-based food. We are aware, that especially in communities like the vegan and organic community, who are trying to base their diets on health-based concepts, GMO-based food, which means food that is either a GMO, contains a GMO or was produced by a GMO, is faced with a lot of, in our opinion unreasonable, stigma. This is especially important, since due to the rising world population, at one point there won’t be enough resources, if we completely rule out the use of GMO-based food.

Overall, we want this project to be a plea for healthy, GMO-based food.

Sources and Literature

[1] Christ, A., Lauterbauch, M., Latz, E. Western lifestyle and the immune system, an inflammatory connection, not published
[2] Mozaffarian, D. (2016). Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review. Circulation 133, 187-225.
[3] Atkinson, F.S., Foster-Powell, K., and Brand-Miller, J.C. (2008). International tables of glycemic index and glycemic load values: 2008. Diabetes Care 31, 2281-2283.
[4] Hosseini, Z., Whiting, S.J., and Vatanparast, H. (2016). Current evidence on the association of the metabolic syndrome and dietary patterns in a global perspective. Nutr Res Rev 29, 152-162.

About iGEM and Team Tübingen

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Software

Throughout our participations in iGEM several software tools have been developed. Read more about them and find download instructions here.

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