Together with the group of Prof. Eicke Latz and iGEM Dresden, we plan to educate about possibilities
that individuals have in order to prevent diseases like type 2 diabetes and adipositas.
Overall, there is more than enough evidence that western life-style, in its sedentary,
high-sugar, high-unsaturated fatty acids, high-cholesterol, high-salt and low-fibre way,
promotes the development of inflammatory and chronic diseases [1,2]. Although, especially in
research environment, this fact is known, knowledge transfer to the public has not been sufficient
enough to adequately spread the notion of a balanced nutrition to prevent potentially fatal diseases,
such as Diabetes Mellitus and Morbus Crohn[1,2,3,4].
As we, iGEM Tübingen, want to target Type 2 DM treatment and iGEM Dresden works on the
development of a new sugar substitution, we want to share our knowledge with the public and start a preventive project.
As our projects are highly intertwined with the use of synthetic biology and the
design and use of GMOs (Genetically modified organisms), we want to combine education
about healthy nutrition, which prevents diseases like Diabetes from occurring solely
because of malnutrition, and the usage of GMO-based food. We are aware, that especially
in communities like the vegan and organic community, who are trying to base their diets
on health-based concepts, GMO-based food, which means food that is either a GMO, contains
a GMO or was produced by a GMO, is faced with a lot of, in our opinion unreasonable, stigma.
This is especially important, since due to the rising world population, at one point there
won’t be enough resources, if we completely rule out the use of GMO-based food.
Overall, we want this project to be a plea for healthy, GMO-based food.
Sources and Literature
 Christ, A., Lauterbauch, M., Latz, E. Western lifestyle and the immune system, an inflammatory connection, not published
 Mozaffarian, D. (2016). Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive
Review. Circulation 133, 187-225.
 Atkinson, F.S., Foster-Powell, K., and Brand-Miller, J.C. (2008). International tables of glycemic index and glycemic
load values: 2008. Diabetes Care 31, 2281-2283.
 Hosseini, Z., Whiting, S.J., and Vatanparast, H. (2016). Current evidence on the association of the metabolic syndrome
and dietary patterns in a global perspective. Nutr Res Rev 29, 152-162.
About iGEM and Team Tübingen
Read about the iGEM competition and get to know our team!
Throughout our participations in iGEM several software tools have been developed. Read more
about them and find download instructions here.